Methodology

EO’s guidance and care platform is designed to make clinically responsible cannabinoid use accessible to all.

Here’s how the platform works:

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Via the EO website, the patient securely provides a comprehensive profile including their symptoms and cannabis use goals, relevant aspects of their medical record, cannabis use history and daily schedule. Baseline symptom-specific and overall well-being PROMIS measures and patient-defined Personally Important Outcomes are also provided.

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This information is then delivered to our clinically validated, rules-based Bayesian guidance engine and combined with all our anonymized and aggregated patient data, relevant medical cannabis research, a comprehensive and proprietary cannabinoid ontology and clinical safety best practices/rules developed by Dr. Brooke Worster, MD, EO’s Chief Medical Officer, and Dr. Benjamin Caplan, MD, EO’s Chief Cannabis Clinician.

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All patient profiles are screened for any symptoms, medications and/or other clinical criteria that might suggest:

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• A human clinician review is warranted before the care plan is provided to the patient.

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• Cannabinoid-based treatments may not be appropriate and the patient should consult with their clinician before proceeding.

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Once screened, our models generate a set of personalized product, dose and use guidance recommendations. These recommendations are then provided to a trained Large Language Model (LLM) AI that translates model outputs into clear, useful text, including detailed and personalized descriptions for why specific recommendations were made. Note that the LLM AI makes no recommendations itself. That work is done by the trained, rules-based Bayesian models, which allows for a clear understanding of recommendation causation.

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The plan is then provided to the patient for review and the patient is encouraged to provide any feedback to our clinician-led team via our HIPAA-compliant in-app messaging. If any relevant feedback is provided it’s then fed back into our models and the care plan is updated. If no further plan adjustments are required, the patient can purchase the recommended products from EO’s online store via the shopping cart embedded in the plan.

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The patient then uses the products as directed and provides feedback via brief check-in surveys accessed within the online care plan. These check-ins allow us to assess patient progress and care plan performance via qualitative measures of product, dose and use guidance efficacy and satisfaction, and updated PROMIS and Personally Important Outcome metric inputs.

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This feedback is then communicated to our data models and the patient’s product dose and use guidance recommendations are modified as appropriate.

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The patient has the option to message EO’s clinical team or call our patient support line whenever they like should any questions or concerns arise between check-ins.
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Please note: No one cannabis treatment plan is effective to treat any particular condition in all circumstances, nor is the efficacy of various treatments necessarily the same between patients.

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Patients: Please consult with your physician before beginning any cannabis care regimen or cannabis treatments. Check with your state and city laws to confirm the legality of cannabis where you live. By creating an account you are confirming that you’re over 21 years of age.