Can Cannabis Help with Nausea? The Effects of THC & CBD on Nausea Relief.
Discover how cannabis can help relieve nausea. Learn how THC and CBD work, what the research says, and how to use them safely and effectively.

Restful sleep isn't just a luxury – it's essential for overall health, affecting everything from mental clarity to immune function. Unfortunately, for a number of people, quality sleep often becomes elusive. Older adults commonly grapple with disruptions caused by chronic pain, anxiety, medications and exposure to blue-light from phones and computers, all of which can sabotage restful nights. While many turn to prescription sleep aids for relief, concerns about dependency, cognitive impairment and potential side effects lead an increasing number of people to seek natural alternatives, like cannabis.
Cannabis has emerged as a promising sleep aid. Known for its calming and sedative effects, THC (tetrahydrocannabinol), the primary psychoactive compound in cannabis, may help users fall asleep faster and achieve deeper, uninterrupted sleep.
In this blog, we'll explore the importance of sleep, how THC and other cannabinoids can gently address modern sleep challenges, how it compares to traditional sleep medications and how to use cannabis products responsibly to get deep, restful sleep.
At EO, we’re working to help cannabis find its place as a responsibly provided, evidence-based medical treatment. We’re led by medical doctors, healthcare professionals and cannabis industry leaders, and our clinical team has deep experience in supportive oncology. We provide affordable, federally legal medical and wellness cannabis products.
Sleep is a fundamental component of overall health, profoundly impacting physical, mental and emotional well-being. High-quality sleep supports immune function, cognitive performance and mood regulation. Conversely, chronic sleep deprivation is linked to increased risks of heart disease, hypertension, obesity, diabetes and impaired immune function.
Research underscores the importance of consistent, quality sleep in maintaining optimal physical and cognitive health. Insufficient sleep has been linked to heightened inflammation, impaired immune response and elevated stress hormone levels, contributing to chronic illnesses such as cardiovascular disease, diabetes and obesity.
Cognitively, quality sleep is essential for memory consolidation, concentration and decision-making. Deep sleep, particularly slow-wave sleep, plays a critical role in memory formation, neural restoration and emotional processing. Chronic sleep deprivation can accelerate cognitive decline, negatively impacting memory, attention and overall cognitive performance.
Sleep also significantly affects emotional health. Chronic sleep disturbances are strongly correlated with increased anxiety, depression and stress. Conversely, improving sleep quality can dramatically enhance mood stability, emotional resilience and overall mental well-being.
In essence, prioritizing sleep is crucial not only for immediate restorative benefits but for protecting long-term health and quality of life.
THC interacts directly with the body's endocannabinoid system (ECS), a network crucial for regulating several physiological processes, including sleep. THC binds primarily to cannabinoid receptor type 1 (CB1), influencing the central nervous system and promoting relaxation and sedation, which are integral for restful sleep.
The ECS helps maintain our body's natural sleep-wake cycle (circadian rhythm). By interacting with CB1 receptors, THC can positively impact how quickly we fall asleep, our depth of sleep and overall sleep quality.
Research indicates that THC may reduce sleep latency, the time required to fall asleep and increase slow-wave sleep, the deepest and most restorative sleep stage. Deep sleep supports physical recovery, immune function and memory consolidation.
However, THC can also have negative effects on REM sleep, often suppressing it. REM sleep is associated with vivid dreams and plays a vital role in processing emotions and memories. A lack of REM sleep can lead to fatigue, mood changes and can even impact cognitive functioning if suppressed long-term.
Clinical studies increasingly support THC as a potential treatment for sleep disorders like insomnia and sleep apnea. For example, research highlights THC's effectiveness in reducing insomnia symptoms by shortening sleep latency and increasing sleep duration.
Cancer patients and chronic pain sufferers often struggle with disrupted sleep. Studies indicate THC's effectiveness in improving sleep quality by providing relief from pain and anxiety, which can be key factors in sleep disruption and poor quality sleep.
Additionally, cannabinoids like CBD and CBN complement THC's sleep-enhancing effects. CBD, a non-psychoactive cannabinoid found in cannabis, can aid relaxation and anxiety reduction, while CBN may provide sedative properties, potentially extending restful sleep durations.
Tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis, has increasingly become recognized for its beneficial effects on sleep. THC interacts directly with the endocannabinoid system, particularly with cannabinoid receptor type 1 (CB1), influencing sleep regulation and promoting relaxation.
Research has demonstrated that THC significantly reduces sleep latency (the time it takes to fall asleep) and enhances slow-wave sleep (deep sleep), crucial for physical restoration and memory consolidation. However, THC also suppresses REM sleep, associated with dreaming and emotional processing. While this can reduce nightmares and disruptive dreams, long-term REM suppression could potentially affect memory and emotional health.
Clinical studies suggest THC is especially beneficial for people experiencing insomnia due to anxiety, chronic pain or medical conditions such as cancer. When used responsibly and at therapeutic doses, THC can significantly improve overall sleep quality, aiding both physical and emotional recovery.
Cannabidiol (CBD), another prominent cannabinoid found in cannabis, is also gaining attention for its potential sleep-promoting properties. Unlike THC, CBD is non-psychoactive, making it a favorable option for those who want to avoid THC’s intoxicating effects.
CBD primarily works by interacting with the body's endocannabinoid system, particularly influencing serotonin receptors, which play an important role in mood and sleep regulation. Research indicates that CBD can reduce anxiety, a common barrier to quality sleep, and help regulate sleep cycles.
While studies suggest that CBD may improve sleep indirectly by alleviating underlying causes of poor sleep, such as anxiety and chronic pain, direct research on CBD’s effectiveness specifically for sleep disorders remains ongoing, highlighting the need for further studies to fully understand its potential benefits and optimal dosing.
CBD’s potential as a safe, non-intoxicating sleep aid makes it an attractive complement to THC, especially for those seeking a holistic approach to improving sleep quality and overall health.
Cannabinol (CBN) is another cannabinoid gaining recognition for its potential as a sleep enhancer. CBN results from the oxidation of THC, and is generally found in aged cannabis.
Emerging research suggests that CBN may possess sedative properties, particularly when combined with THC or CBD. Research indicates that CBN may interact with the endocannabinoid system to enhance relaxation and sedation, potentially improving sleep quality and duration.
While clinical research on CBN remains limited compared to THC and CBD, anecdotal evidence and preliminary studies show promise, suggesting that CBN might help reduce sleep latency and promote deeper, more restful sleep. As research expands, CBN appears primed to become a valuable part of the holistic approach to sleep management with cannabis.
Prescription sleep aids, such as Ambien or benzodiazepines, typically work by depressing central nervous system activity, quickly inducing sleep. However, these medications frequently come with risks, including dependency, withdrawal symptoms, cognitive impairment, memory loss, dizziness, daytime drowsiness and increased risk of falls, particularly among older adults.
Prescription sleep medications, while effective short-term, may negatively impact sleep architecture. For instance, benzodiazepines can reduce restorative deep sleep and REM sleep, contributing to poorer overall sleep quality over time. Long-term use is associated with cognitive decline, confusion and higher risk of accidents, including falls and motor vehicle incidents.
Over-the-counter sleep aids like antihistamines (e.g., diphenhydramine) also carry potential drawbacks, including daytime grogginess, cognitive impairment and dizziness, especially among older adults. Prolonged use has been linked to an increased risk of dementia, further highlighting the dangers of regularly relying on these medications as a sleep aid.
THC, by contrast, has shown potential as a sleep aid with fewer severe side effects when used responsibly and in moderation. While THC may also carry risks of cognitive impairment and dependency, its side effects are typically milder and less severe than prescription medications. Furthermore, THC rarely results in severe withdrawal symptoms or long-term cognitive issues when used at therapeutic, low doses.
Unlike many pharmaceutical sleep aids, THC has been shown to enhance the natural sleep process by increasing the amount of slow-wave sleep (deep sleep), contributing to better overall restorative sleep quality. Additionally, THC's efficacy in improving sleep often comes paired with therapeutic benefits, such as reduced anxiety, pain relief and decreased inflammation – benefits traditional sleep aids typically do not provide.
Ultimately, THC offers a holistic alternative to traditional sleep medications. Used responsibly and in moderation, THC can be a safer, effective part of a comprehensive sleep strategy, complementing practices like good sleep hygiene, mindfulness, relaxation exercises and consistent sleep schedules.
Several THC delivery methods are available, each offering different benefits, drawbacks, onset times and duration:
The best way to get started is to start low (dose) and slow. Initial doses of 2.5-5 mg THC are usually effective for sleep enhancement. Adjusting gradually can help avoid unwanted side effects like grogginess or cognitive impairment the next day.
Ideally, take your preferred method of THC about one hour before bedtime to align its peak effects with your bedtime routine.
Like any sleep aid, THC use involves potential side effects, however these are typically mild and dose-dependent:
These side effects can often be mitigated by starting with the lowest effective dose and gradually adjusting based on what works best for you.
High THC doses may worsen sleep quality or cause paradoxical anxiety in some users. Regular long-term use can also lead to tolerance, requiring higher doses over time, and dependence, making it harder to fall and stay asleep naturally.
Withdrawal from THC might include difficulty sleeping, vivid dreams or increased anxiety. Receiving professional dosing guidance significantly reduces these risks by tailoring THC use to your needs and minimizing tolerance or dependence.
Cannabis, when used thoughtfully and responsibly, can significantly enhance sleep quality, reduce sleep disturbances and offer a natural alternative to traditional sleep medications. While the benefits are promising, users should remain mindful of potential risks. By starting with low doses, understanding delivery methods and utilizing professional guidance, older adults can safely and effectively integrate THC into their sleep routines, enjoying deeper, more restorative sleep.
For cannabis users seeking a healthier and more reliable way to reap the medical benefits of cannabis, consider EO’s Sleep Bundle. Our Sleep Bundle helps relax the mind and body so you can fall asleep faster and get deep, restful sleep. It includes our Guided Bedtime THC gummies, our Guided Rest CBD & CBN Capsules and our Guided Spot Relief precision-dosed topical to help soothe aching joints and muscles.
Most importantly, every EO product comes with free clinician-led guidance via phone or email. Whenever you have questions about how you can put cannabis to work most safely and effectively, the EO team will be there to guide you.
The content on this page is for informational purposes. Do not attempt to self-diagnose or prescribe treatment based on the information provided. Always consult a physician before deciding on the treatment of a medical condition.
Discover how cannabis can help relieve nausea. Learn how THC and CBD work, what the research says, and how to use them safely and effectively.
Explore how THC can help relieve pain, what the science says, how it compares to traditional treatments, and tips for using it responsibly.
Navigating a cancer diagnosis is one of the most difficult life challenges a person can face. Two-time cancer survivor and EO spokesperson Ethan Zohn says, “cancer is a disease that touches every part of you as a human being: mental, physical, social, spiritual. You’re always just looking for ways to make yourself feel better.”
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